Discover a controlled-release drug delivery system purpose-built for ruminants. Argenta's intraruminal capsule technology delivers consistent API release for up to 343 days from one administration, with the flexibility to treat multiple conditions in a single device.
ranging from 20kg lambs to 800kg cattle
across four continents with a track record of regulatory success.
across North America, Europe, Australia/NZ, and Asia
A controlled-release capsule (CRC) is an orally administered therapeutic delivery device engineered specifically for ruminant animals. Dosed using an applicator, the device resides in the animal's rumen where it delivers a consistent, controlled release of API.
To ensure consistent delivery, three components work together:
Unlike conventional dosing methods, CRCs deliver API at a constant, zero-order rate for the full dosing period. Studies have demonstrated minimal variability in therapeutic payout across 343 days, providing livestock farmers with the confidence that every animal in a herd is receiving the right dose at the right time.
For intensive farming operations and pasture-grazing livestock, where repeated medication administration is a major logistical challenge, the one-shot nature of CRCs reduces the need to round up and handle animals to just once or twice per year, saving significant time, cost, and inconvenience.
CRCs can be engineered with a pulse-release system, enabling time-targeted treatments throughout the year from a single device. By alternating blank (excipient-only) and active (API-containing) tablets within the product core, developers can deliver drug combinations, build in washout periods, or administer multiple APIs on different timelines.
This flexibility makes CRCs particularly valuable for parasite control programmes, combination therapy protocols, and any indication requiring precise, sequential dosing over an extended period.
We manufacture controlled-release intraruminal capsules at our EMA- and FDA-approved GMP facility in Auckland, New Zealand — home to unique gel-former technology, dedicated production lines, and end-to-end support from lab scale through to commercial supply.
Our CRC products are manufactured at both lab and production scales, with automated assembly capabilities and granules produced in a range of sizes to precisely tailor API release profiles to your therapeutic goals.
